Pfizer says its COVID vaccine is safe for kids aged 5 to 11

Pfizer-BioNTech announced on Monday that their COVID-19 vaccine is safe and effective among children between ages five and 11. 

Data from late-stage clinical trials showed that the vaccine – which was given in a smaller dose – induced a ‘robust’ immune response among youngsters during late-stage clinical trials.

Levels of neutralizing antibodies among five-to-11 year-olds were similar to those seen 16-to-25 year-olds, the companies said in a press release

Pfizer scientists also described the vaccine as being ‘safe and well-tolerated’ in children under age 12.

The U.S. pharmaceutical giant and its German partner firm said they plan to apply for emergency use authorization with the U.S. Food and Drug Administration (FDA) this month and will also soon seek authorization in Europe. 

This means that, if the FDA determines the shot is safe and effective, kids may be authorized to receive the vaccine by Halloween. 

Parents are split 50/50 about whether or not they will inoculate their children because COVID-19 cases are generally mild in children and pediatric deaths make up just 0.1 percent of all Covid deaths. 

Pfizer announced Monday that its COVID vaccine is safe for children aged between five and 11

Pfizer announced Monday that its COVID vaccine is safe for children aged between five and 11

Pfizer announced Monday that its COVID vaccine is safe for children aged between five and 11

‘We are pleased to be able to submit data to regulatory authorities for this group of school-aged children before the start of the winter season,’ said Dr Ugur Sahin, CEO and co-founder of BioNTech in the press release. 

The safety profile and immunogenicity data in children aged five to 11 years vaccinated at a lower dose are consistent with those we have observed with our vaccine in other older populations at a higher dose.’     

According to clinicaltrials.gov, Pfizer’s study in younger children worked similarly to the way it did in older children and adults.

About half of the ages five-to-11 group were given two doses 21 days apart and the other half were given placebo shots.

The team then tested the safety, tolerability and immune response generated by the vaccine, likely by measuring antibody levels in the young subjects

COVID-19 hospitalizations and deaths have surged in the United States in recent months due to the highly contagious Delta variant. Pediatric cases are also up, particularly as children under 12 are all unvaccinated, but there is no indication that, beyond being more transmissive, the Delta virus is more dangerous in kids.

A rapid authorization could help mitigate a potential surge of cases in the fall, especially with schools already open nationwide.

The companies’ vaccine, called Comirnaty, is already authorized for use in children as young as 12 in many countries, including the United States. The vaccine was originally authorized for emergency use in people 16 or older in the United States in December 2020 and received full U.S. approval in that age group last month.

The 5-to-11 year olds were given two shots of a 10-microgram dose of the vaccine, one-third the dose size that has been given to people 12 and older. 

The companies expect data on how well the vaccine works in children 2-to-5 years of age and children 6 months-to-2 years of age as soon as the fourth quarter of this year.

Unlike the larger clinical trial the drugmakers previously conducted in adults, the 2,268 participant pediatric trial was not primarily designed to measure the vaccine’s efficacy by comparing the number of COVID-19 cases in vaccine recipients to those who received a placebo.

Instead, the trial compares the amount of neutralizing antibodies induced by the vaccine in the children to the response of older recipients in the adult trial.

A Pfizer spokesperson said the companies may later disclose vaccine efficacy from the trial but there had not been enough cases of COVID-19 yet among the participants to make that determination.

The vaccine was around 95 percent effective in the adult clinical trial, but Pfizer has said that immunity wanes some months after the second dose. U.S. regulators are expected to authorize a third, booster dose of the vaccine for older and high-risk Americans early this week.

The companies said the vaccine was well-tolerated, with side effects generally comparable to those observed in participants 16 to 25 years of age.

Both the Pfizer and Moderna vaccines have been linked by regulators to rare cases of heart inflammation in adolescents and young adults, particularly young men. Pfizer said they did not see any instances of heart inflammation in the trial participants.

However, despite promising results, many parents are not enthusiastic about vaccinating their children.

In a recent poll, conducted by the Kaiser Family Foundation, parents were asked if they would get their child immunized once a COVID-19 vaccine is authorized and available for their child’s age group.

Only about three in 10 parents – 29 percent – of children under 18 said they would get their child vaccinated ‘right away.’

The poll also found 15 percent only plan to vaccinate their children if the school requires it and 19 percent said their child will definitely not be getting vaccinated.

What’s more, although children can contract COVID-19 and pass the disease on to others, they tend to not get very ill.

Link hienalouca.com

Advertising:

Tips to Find Low Priced Luxury Holiday Package Deals Fast

For most families, it has already been a common practice to spend the Holiday season in a foreign location. This is caused by the aviation market changes which have given a lot of benefits for people who travel a lot. Airfares going to different tourist destinations are becoming more inexpensive. What does this mean? If there is a perfect time to purchase luxury holiday package deals, now it the right time! Based on the market trend nowadays, you can save both money and time when you go for a luxury holiday. There are countless offers that combine travel and accommodation in one package which is a lot cheaper than getting separate deals. Aside from that, it is also risky to individually book the services that you need for the vacation. You might end up missing out on some important details of the trip. Unlike when you take advantage of luxury holiday package deals, you can be sure that everything is organized meticulously and according to what you really need. Nonetheless, you would still need to carefully select the package that would fit your needs. Review the following tips in getting packages that are reasonably priced. · Normally, luxury tour packages include accommodation, flight travel and transportation to individual tourist destinations. It would be best to choose the complete package so you won’t have to worry about other vacation elements. In addition to that, these are the packages that have the biggest discounts. · You can get big mark down prices, if you will purchase more packages. It is not a bad idea to share the wonderful moment with your loved ones. By doing so, you would not only enjoy, you will also save more money. You can even use your savings for other activities on your vacation. · It would be best to know how much you are willing to pay for the luxury tour packages. You can already work around your budget. You have to stick to your budget. If not, you might end up spending a lot and you will be left with less money for your vacation. · Prices may vary depending on the destination of the tour. You can do a research about places that are attractive yet inexpensive. There are thousands of destinations and you just have to choose wisely. · There are packages that include recreational activities. This means that you are paying for all the activities when you purchase these packages. The right thing to do is to make sure that the activities that are included would be the ones that you really enjoy. There is no sense in paying for activities that will not really make your vacation memorable. If you are going with friends, you should also consider their preferences so that you can be sure that everyone will enjoy the trip. There are other ways on how you can be sure that you are getting the best deal for your luxury holiday vacation. No matter how you choose to do it, you have to get adequate information about the packages. This will help you determine whether it is worth the price.

(Total views: 52 Time, 1 visits per day)

Leave a Reply