The 48-year-old revealed his diagnosis on Friday – eight days before he was scheduled to step into the ring to take on former UFC champion Vitor Belfort at the Staples Center in Los Angeles.
De La Hoya announced he had contracted the coronavirus despite being fully vaccinated.
He shared a video to Twitter from his hospital bed and stated: ‘I wanted you to hear directly from me that despite being fully vaccinated, I have contracted Covid and am not going to be able to fight next weekend.
‘Preparing for this comeback has been everything to me over the last months, & I want to thank everyone for their tremendous support.’
The comeback fight against Belfort was schedule to be De La Hoya’s first professional fight since he announced his retirement back in 2009.
Professional boxer Oscar De La Hoya has withdrawn from his upcoming comeback fight after testing positive for COVID-19. He is pictured at a media event in Los Angeles last week
De La Hoya shared a video from his hospital bed on Friday after contracting COVID-19