Moderna’s vaccine is 90% effective at protecting against infection six months after the final dose

Moderna Inc says its vaccine is more than 90 percent effective at protecting against COVID-19 six months after the second dose.

In updated data from its phase III clinical trial published on Tuesday, the company also said its jab is more than 95 percent effective against severe disease 24 weeks after receiving the final dose.

The new data brings Moderna closer to filing for full approval with the U.S. Food and Drug Administration (FDA)

The vaccine was approved for emergency use in those aged 18 and older in December 2020 but with just two months of safety data. 

Although the level of efficacy is slightly lower than the 94.5 percent reported last year, the data show the vaccine provides long-term protection.

New data from Moderna's phase III clinical trial showed its vaccine is 90% effective at preventing COVID-19 infection six months after the second dose. Pictured: A healthcare worker holds a vial of the Moderna COVID-19 vaccine in New York City, January 2021

New data from Moderna's phase III clinical trial showed its vaccine is 90% effective at preventing COVID-19 infection six months after the second dose. Pictured: A healthcare worker holds a vial of the Moderna COVID-19 vaccine in New York City, January 2021

New data from Moderna’s phase III clinical trial showed its vaccine is 90% effective at preventing COVID-19 infection six months after the second dose. Pictured: A healthcare worker holds a vial of the Moderna COVID-19 vaccine in New York City, January 2021

The shot was also more than 95% at preventing severe disease six months out, as the U.S. vaccination campaign continue to ramp up

The shot was also more than 95% at preventing severe disease six months out, as the U.S. vaccination campaign continue to ramp up

The shot was also more than 95% at preventing severe disease six months out, as the U.S. vaccination campaign continue to ramp up

The updated data comes after a study published in the New England Journal of Medicine by a team from Duke University showed antibodies generated by the Moderna vaccine were still present six months after the final dose.

These are very similar to findings reported by Pfizer-BioNTech which uses similar technology to their vaccine. 

The new data looked at 900 cases of COVID-19 reported among Moderna’s late-stage clinical trial participants.

However, the Cambridge, Massachusetts-based company did not specify how many of those cases were in vaccine recipients and how many were in the placebo group. 

Moderna is still running several vaccine trials including on children aged 17 and younger and testing vaccine booster.

The trial involving children between ages 12 to 17 is now fully enrolled with about 3,000 participants in the U.S.

Meanwhile, the trial of those from six months to 11 years old is currently enrolling and is expected to be capped at 6,750 participants in the U.S. and Canada.  

Additionally, earlier this month, the National Institutes of Health (NIH) began early-stage clinical trials testing a booster shot of Moderna Inc’s coronavirus vaccine to see if it provides better protection against the highly contagious variant from South Africa.

Approximately 210 healthy adult volunteers will be enrolled at four clinical research sites in the Atlanta, Cincinnati, Nashville and Seattle areas.

In the new study, volunteers will receive three types of booster shots, which are modified versions of Moderna’s original vaccine.

One-third of participants will receive 50 micrograms (µg) of the booster candidate, which has been dubbed mRNA-1273.351.

Another-third will receive a higher dose, 100 µg, of the candidate.

The last group will be given a shot called mRNA-1273.211, which combines Moderna’s original vaccine and the booster shot in one dose.

The updated data comes after a study showed antibodies generated by the Moderna vaccine were still present six months after the final dose (above)

The updated data comes after a study showed antibodies generated by the Moderna vaccine were still present six months after the final dose (above)

The updated data comes after a study showed antibodies generated by the Moderna vaccine were still present six months after the final dose (above)

Researchers will evaluate the safety of the booster as well as whether or not it is able to induce an immune response.

They will also look at potential side effects including redness and pain at the injection site, fever, headache, fatigue and muscle aches.

‘The Moderna team continues to make important progress with our COVID-19 Vaccine,’ said CEO Stéphane Bancel in a statement.

‘We are looking forward to having the clinical data from our variant-specific booster candidates, as well as clinical data from the Phase 2/3 study of our COVID-19 Vaccine in adolescents, 

‘The new preclinical data on our variant-specific vaccine candidates give us confidence that we can proactively address emerging variants. Moderna will make as many updates to our COVID-19 vaccine as necessary until the pandemic is under control.’   

Link hienalouca.com

Advertising:

Tips to Find Low Priced Luxury Holiday Package Deals Fast

For most families, it has already been a common practice to spend the Holiday season in a foreign location. This is caused by the aviation market changes which have given a lot of benefits for people who travel a lot. Airfares going to different tourist destinations are becoming more inexpensive. What does this mean? If there is a perfect time to purchase luxury holiday package deals, now it the right time! Based on the market trend nowadays, you can save both money and time when you go for a luxury holiday. There are countless offers that combine travel and accommodation in one package which is a lot cheaper than getting separate deals. Aside from that, it is also risky to individually book the services that you need for the vacation. You might end up missing out on some important details of the trip. Unlike when you take advantage of luxury holiday package deals, you can be sure that everything is organized meticulously and according to what you really need. Nonetheless, you would still need to carefully select the package that would fit your needs. Review the following tips in getting packages that are reasonably priced. · Normally, luxury tour packages include accommodation, flight travel and transportation to individual tourist destinations. It would be best to choose the complete package so you won’t have to worry about other vacation elements. In addition to that, these are the packages that have the biggest discounts. · You can get big mark down prices, if you will purchase more packages. It is not a bad idea to share the wonderful moment with your loved ones. By doing so, you would not only enjoy, you will also save more money. You can even use your savings for other activities on your vacation. · It would be best to know how much you are willing to pay for the luxury tour packages. You can already work around your budget. You have to stick to your budget. If not, you might end up spending a lot and you will be left with less money for your vacation. · Prices may vary depending on the destination of the tour. You can do a research about places that are attractive yet inexpensive. There are thousands of destinations and you just have to choose wisely. · There are packages that include recreational activities. This means that you are paying for all the activities when you purchase these packages. The right thing to do is to make sure that the activities that are included would be the ones that you really enjoy. There is no sense in paying for activities that will not really make your vacation memorable. If you are going with friends, you should also consider their preferences so that you can be sure that everyone will enjoy the trip. There are other ways on how you can be sure that you are getting the best deal for your luxury holiday vacation. No matter how you choose to do it, you have to get adequate information about the packages. This will help you determine whether it is worth the price.

(Total views: 45 Time, 1 visits per day)

Leave a Reply