A mutated strain of
The new Covid-19 variant — called Cluster 5 — caused global panic after it was found to be resistant to antibodies, substances made by the body to fight off infections.
It was feared Cluster 5 would be able to slip past promising new Covid-19 vaccines, which work by stimulating an antibody response.
Officials locked down swathes of northern Denmark where the strain originated and ordered the culling of 17million mink earlier this month in a bid to stomp out the variant before it became widespread.
In a statement today, the country’s health ministry said there had been ‘no new cases of Cluster 5 since September 15’ which led it to conclude it ‘has most likely been eradicated’.
Scientists believe the mutant virus jumped from fur farm workers to mink in the summer before it was passed back to humans. As it crossed between species, a mutation occurred on its ‘spike’ protein, which it uses to enter human cells. It was significant because the leading vaccine candidates work by targeting this protein.
When news about the new strain broke earlier this month, Britain banned non-British citizens returning from Denmark and introduced strict quarantine rules for any Brit who’d recently returned from the country.
At the time, UK Health Secretary Matt Hancock warned the mutated could have ‘grave consequences’ if it became widespread.
A mutated strain of coronavirus that emerged in mink and could make vaccines less potent has been eradicated, officials in Denmark claimed today
Danish officials ordered the culling of 17million mink earlier this month in a bid to stomp out the strain before it become widespread
The Danish health ministry said in a statement today: ‘There have been no new cases of the Cluster 5 mink mutation since September 15, which has led to the Danish infectious disease authority SSI to conclude that this variant has most likely been eradicated.’
The Government said most of the strict lockdown rules imposed on November 5 on seven municipalities in North Jutland would be lifted on Friday. They had originally been due to stay in place until December 3.
Cluster 5 has only been found in 13 people living in the region, which is home to 280,000 people.
All minks in the seven municipalities have been culled, totalling 10.2 million, and the slaughter is still ongoing in other parts of the country.
With three times more minks than people, the Scandinavian country is the world’s biggest exporter, selling pelts for around £596million ($792m) annually, and the second-biggest producer behind China.
Farmers living in regions of Denmark not affected by the mutated strain of Covid-19 are still allowed to sell mink fur — but must still kill all their livestock this month.
Five different strains of mutant mink coronavirus have been spotted in 214 people in Denmark since June.
Analysis by Denmark’s State Serum Institute revealed only Cluster 5 was less sensitive to antibodies.
Antibodies are disease-fighting proteins made and stored by the immune system to fight off invaders in the future by latching onto their spike proteins.
But if they are unable to recognise proteins because they have mutated, it means the body may struggle to attack a virus the second time and lead to a second infection.
It raised fears the new strain could be harder to treat or vaccinate against.
It is not uncommon for viruses to be able to jump between humans and other animals – which was also the case for H5N1, or bird flu, and H1N1, swine flu.
The sole purpose of any virus is to replicate as many times as possible. So when a virus jumps from one species to another it naturally mutates to adapt to a new host.
With Covid-19, tiny changes in its DNA occurred when it was passed to mink. It means that when the virus was passed back to humans its biology was different, so it may behave differently to other strains while inside humans.
WHAT IS THE NEW COVID-19 STRAIN AND SHOULD YOU BE WORRIED?
What is going on in Denmark?
The coronavirus which originated in China and is currently racing through the world’s population was passed from humans to mink.
When it entered the mink population the virus was forced to mutate to multiply inside its new host and spread among the animals, creating a new strain.
At some point this new variant was then passed back to humans.
Should we be worried?
So far experts believe the new strain – known as Cluster 5 – is not more infectious or deadly than previous versions.
But there is a concern that it is less sensitive to antibodies – substances produced by the immune system to fight off infections.
Vaccines work by training the body to be able to unleash a wave of antibodies when the virus tries to infect people.
This has raised concerns that it might render any future Covid-19 vaccine less effective if it were to spread.
Danish specialists have warned it could theoretically start a new pandemic.
How did it happen?
All viruses naturally mutate as they spread.
The sole purpose of the virus is to replicate as many times as possible, and many pathogens evolve over time in order to become more infectious — which often makes them less deadly so they can survive for longer and be spread to more people.
It is believed SARS-CoV-2 originated in bats before jumping to humans in China, possibly via an intermediary species such as a pangolin.
Mink in Denmark are believed to have caught the virus from infected workers at fur farms.
The virus then mutated in the minks before ‘spilling back’ to reinfect humans.
Are there any mink in the UK?
The risk of something similar happening in the UK is low because fur farming has been banned here since 2002.
There are populations of wild mink in the UK after they were shipped over from America for fur farming decades ago.
But people rarely come into close contact with wild mink, meaning the threat of Covid-19 transmission is low.