Jon Cryer is handcuffed as Lex Luther during his first appearance on set to film Supergirl

Fans have eagerly awaited Jon Cryer’s turn as Superman’s arch enemy Lex Luthor.

And the anticipation will soon be over as the veteran actor was spotted on set of Supergirl in Vancouver on Saturday.

The 53-year-old rocked the iconic bald look as he was handcuffed in a grey jumpsuit being led by two police officers.

Super villian: Jon Cryer was spotted as Lex Luther on set of Supergirl in Vancouver on Saturday

Super villian: Jon Cryer was spotted as Lex Luther on set of Supergirl in Vancouver on Saturday

Super villian: Jon Cryer was spotted as Lex Luther on set of Supergirl in Vancouver on Saturday

Cryer kept in character as he looked downtrodden during the shoot with the armed guards man handling him.

Cryer will make his debut in the 15th episode of the show’s current fourth season.

In the episode entitled – O Brother, Where Art Thou? – Luthor reaches out from prison to enlist Lena (Katie McGrath) into one of his plans and will stop at nothing to get her on board, even if that means leveraging the life of one of her friends.

Originally introduced as a mad scientist, Alexander Joseph ‘Lex’ Luthor, first appeared in action comics #23, and has persisted as Superman’s arch rival ever since.

Iconic: The 53-year-old rocked the iconic bald look as he was handcuffed in a grey jumpsuit being led by two police officers

Iconic: The 53-year-old rocked the iconic bald look as he was handcuffed in a grey jumpsuit being led by two police officers

Iconic: The 53-year-old rocked the iconic bald look as he was handcuffed in a grey jumpsuit being led by two police officers

Sneak peek: The actor has a recurring role in the fourth season of Supergirl

Sneak peek: The actor has a recurring role in the fourth season of Supergirl

Sneak peek: The actor has a recurring role in the fourth season of Supergirl

Lex has been portrayed as a wealthy, power-mad American business magnate, engineer and philanthropist to the city of Metropolis, as well as one of the most intelligent people in the world.

Traditionally, the character doesn’t have any superpowers, or alter-identity, and typically appears with a bald head.

This isn’t Cryer’s first foray into the DC Universe; he played Lenny, Lex’s nephew, in the 1987 film Superman IV: The Quest for Peace, alongside Gene Hackman.

‘We are enormous fans of Jon Cryer, and he was instantly our dream actor to play the iconic role of Lex Luthor,’ said executive producers Robert Rovner and Jessica Queller.

Superhero: Melissa Benoist has starred as the superheroine, Supergirl, since 2015

Superhero: Melissa Benoist has starred as the superheroine, Supergirl, since 2015

Superhero: Melissa Benoist has starred as the superheroine, Supergirl, since 2015

Coming soon: Jon Cryer makes his debut as Lex Luthor in episode 15 of the current season of Supergirl, which airs March 17, on The CW

Coming soon: Jon Cryer makes his debut as Lex Luthor in episode 15 of the current season of Supergirl, which airs March 17, on The CW

Coming soon: Jon Cryer makes his debut as Lex Luthor in episode 15 of the current season of Supergirl, which airs March 17, on The CW

‘Jon is a super-talent, and the fact that he played Lenny Luthor in Superman IV brings an added layer of legacy to his casting. We’re beyond thrilled to welcome Jon to the Supergirl family.’

The actor is best known to fans as Alan Harper on the hugely successful sitcom Two and a Half Men, which aired from 2003-2015 and landed him two Emmy Awards.

Jon Cryer makes his debut as Lex Luthor in Supergirl, March 17, on The CW.

Cryer is best known as Alan Harper on the hit sitcom Two and a Half Men from 2003-2015

Cryer is best known as Alan Harper on the hit sitcom Two and a Half Men from 2003-2015

Cryer is best known as Alan Harper on the hit sitcom Two and a Half Men from 2003-2015

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