Motor Neurone Disease breakthrough: ‘Remarkable’ new drug can slow down the disease by 70 per cent

Australian researchers are optimistic that a new copper capsule may offer Motor Neurone Disease sufferers hope for a cure. 

The drug, CuATSM, was trialled on 32 patients in Melbourne and Sydney over 15 years, and appeared to ­slow the progression of MND by 70 per cent.

It is based on the theory that a decrease of copper in the brain may be a factor in the onset of neurodegenerative diseases 

A new copper drug by Australian researchers has been found to slow the progression of MND

‘Copper is just part of the drug,’ Professor Ashley Bush, ­director of the Florey Institute of Neuroscience and Mental Health told The Daily Mail.

‘We are working out what the mechanism is now, but the possibilities include delivering a safe amount of copper to where it is needed in the tissue, as well as, mopping up damage to the membranes of neurons, or both.’ 

The breakthrough is particularly exciting as it is the first of its kind which appears to slow the progression of the disease, rather than just treat the symptoms. 

‘For a disease that is considered irreversible it was remarkable,’ said Professor Bush. 

‘The approach is to try to stop the disease, rather than provide symptomatic benefit.’  

Professor Ashley Bush is optimistic the findings could pave the way for a cure for MND

Professor Ashley Bush is optimistic the findings could pave the way for a cure for MND

Professor Ashley Bush is optimistic the findings could pave the way for a cure for MND

The study was conducted by researchers from the Florey Institute, the University of Melbourne and the Bio21 Institute of Molecular Science and Biotechnology.

Findings were presented at at the International Symposium on ALS/MND in Glasgow, Scotland, with a second phase trial scheduled for the second half of 2019. 

‘Our first study of the drug (which is also currently being tested on patients with Parkinson’s disease) was encouraging’, said Professor Bush. 

‘The plan is to take the next step towards a definitive result, which might take two years to complete.’

Research was partly funded by AFL legend Neale Daniher’s Fight MND Foundation, which contributed $500,000 to the stage 1 trial. 

The former Essendon player was himself diagnosed with MND in 2013, and has since used his platform to raise funds and awareness of the disease.   

MND sufferer and AFL legend Neale Daniher (right) contributed funds towards the research

MND sufferer and AFL legend Neale Daniher (right) contributed funds towards the research

MND sufferer and AFL legend Neale Daniher (right) contributed funds towards the research

 

 

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One comment

  1. I am a 51 year old female that just found out I have Motor Neuron Disease Parkinson’s about a year and half, but I have been having signs of it for years, tremors, depression, body weakness. ECT. I honestly don’t think my doctor was reading the signs because of my gender and age. A few years ago I had my shoulder lock up on me and I was sent to a P.T since x-rays didn’t show any physical damage. My shaking was getting worse and I began falling. Only when my speech became so bad that it brought concern to my dentist was Parkinson’s even considered. He phoned my doctor with his concerns about my shaking and balance problems. By this time I was forgoing shots in the back of my neck for back and neck pain to which once again I was sent to a P.T (although x-rays showed no damage) I was told I had a few spurs which were most likely causing the pain. Here I was feeling like my whole body was falling apart and doctor could not find anything wrong, maybe in was all in my head? My doctor even seemed annoyed with me and things just kept progressing and I just kept it to myself, why bother going through testing and them finding nothing? Well, it was after my second P.T called my doctor about the weakness in my legs and arms, by this time I have developed a gait in my walk and I fell more frequently. Only then did my doctor send me to a specialist and it was found that I had Parkinson’s, and that I have had it for awhile. I think because I was a woman that my signs and symptoms weren’t taken seriously and therefor left untreated for so long,I was taking pramipexole dihydrochloride three times daily, I Was on carbidopa levodopa but only lasted 90 minutes then wore off.I found that none of the current medications worked effective for me.I got tired of using those medication so I decided to apply natural herbs formula that was prescribed to me by my second P.T, i purchase the herbal formula from totalcureherbsfoundation. com, There has been huge progression ever since I start the treatment plan which will last for 15 weeks usage.all the symptoms and sign has begin to disappear .

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